Human Sera
Cayman Chemical BIalaphosodIum salt 100mg
A natural non-selective phytotoxin that is converted in vivo to the active agent phosphinothricin, which inhibits glutamine synthetase (Ki = 6.1 µM); used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter
Cayman Chemical DeXromethorphnhydrobromId 50mg
An analytical reference standard categorized as an antitussive; has analgesic and anticonvulsant activities in rodents; has been found as an adulterant in 3,4-MDMA; has potential for abuse; intended for research and forensic applications
Cayman Chemical LoperamIdehydrochlorIde 50mg
An opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery; has antidiarrheal action; blocks voltage-sensitive sodium channels (IC50 = 270 nM) and high voltage-activated calcium channels (IC50 = 900 nM); comparable to morphine in blocking peripheral pain
Cayman Chemical ClenbuterolhydrochlorIde 100mg
A β2-AR agonist; induces relaxation of equine tracheal muscle strips (EC50 = 2.1 nM); increases the number of autophagosomes and autophagic flux in HepG2 cells at 300 nM; increases blood flow to adipose tissue and induces weight gain in rats at 2 mg/kg; induces relaxation of bovine uterus; inhibits infection of MDCK cells by an H1N1 influenza isolate in vitro (EC50 = 9.4 µM)
Cayman Chemical DGlucosamIn6phosphatehy 100mg
A monosaccharide intermediate of the hexosamine biosynthetic pathway; binds the GlmS riboswitch (Ki = 380 µM) and inhibits GlmS production and decreases D-GlcN-6-P levels; precursor in the biosynthesis of UDP-GlcNAc
Cayman Chemical VelpatsvIr 100mg
An NS5A inhibitor; inhibits replication of HCV genotypes 1-6 (EC50s = 6-130 pM in replicon assays); inhibits SARS-CoV-2 exonuclease activity at 100 µM; enhances remdesivir-induced inhibition of SARS-CoV-2 replication in infected Calu-3 cells at 10 µM
Cayman Chemical N6-MethyladenIn 50mg
A modified purine that is commonly found in genomes of prokaryotes, protists, and plants
Cayman Chemical SBE 13hydrochlorIde 50mg
A potent inhibitor of Plk1(IC50 = 0.2 nM) that targets the inactive conformation of the enzyme; exhibits no activity against aurora A kinase and less effectively inhibites Plk2 (IC50 > 66 µM) and Plk3 (IC50 = 875 nM); induces cell cycle arrest, reduces cell proliferation, and induces apoptosis
Cayman Chemical PyrImethamIn 100mg
A dihydrofolate reductase inhibitor that prevents the production of tetrahydrofolic acid in P. falciparum and other protozoa; displays a prophylactic effect (ED50 = 0.5 mg/kg) in in vivo antimalarial mouse models
Cayman Chemical InosIn 5-trIphosphatesodI 50mg
A nucleoside triphosphate; alternative substrate for ATPases and GTPases; has been used to study activation and binding kinetics of nucleoside interaction with various ATPases and GTPases
Cayman Chemical 15mthyl PalmItIc ACD mthy 50mg
A methylated fatty acid methyl ester; has been found in S. zeai sea sponges as the fatty acyl component of zeamide, oolong tea, and P. sulcate extract
Cayman Chemical NaphthofluoresceIn 50mg
A cell-permeable inhibitor of furin (IC50 = 12 μM); inhibits furin-mediated cleavage of the pro-form of MT1-MMP, resulting in decreased levels of active MT1-MMP; inhibits the invasion of Matrigel by the human fibrosarcoma cell lines HT1080
Cayman Chemical 1MethylnIcotInamIDCLOrId 100mg
An active metabolite of nicotinamide; induces nitric oxide secretion from HUVECs in a concentration-dependent manner; increases plasma levels of 6-keto-prostaglandin F1α in normotensive rats at 30 mg/kg and inhibits collagen-induced thrombus formation in rats at the same dose